5-Chloro-4-Amino-2,1,3-Benzothiadiazole
Key starting material and intermediate for cardiovascular drug synthesis
Technical / Structural Monograph
5-Chloro-4-amino-2,1,3-benzothiadiazole is a heterocyclic organic compound featuring a benzothiadiazole core structure decorated with ortho chloro and amino substituents. This intermediate is valued for its remarkable versatility in multi-step organic synthesis and acts as a central building block for diverse cardiovascular and anti-spasticity agents. Sourced strictly from validated manufacturers.
Synthesis Role & End-Use Applications
A key clinical-grade pharmaceutical intermediate used in the synthesis of various therapeutic compounds. This benzothiadiazole derivative serves as an important building block in drug development and active API manufacturing, produced under stringent conditions with premium quality control.
Typical Quality Specification
| Test Parameter | Specification | Method |
|---|---|---|
| Appearance | Yellow to orange-brown crystalline powder | — |
| Purity | ≥98.0% | GC/HPLC |
| Assay / Purity | ≥98.0% | GC/HPLC |
| Single Maximum Impurity | < 0.1% | — |
| Total Impurities | < 0.5% | — |
| Heavy Metals | < 10 ppm | — |
| Sulfated Ash | < 0.1% | — |
Packaging & Storage
Double LDPE bags
Store at room temperature 15-30°C (59-86°F)
24 months when stored under recommended, un-opened container parameters